The inheritance of enzyme variants of glutamic-oxaloacetic transaminase in Paragonimus ohirai
Identifieur interne : 003454 ( Main/Exploration ); précédent : 003453; suivant : 003455The inheritance of enzyme variants of glutamic-oxaloacetic transaminase in Paragonimus ohirai
Auteurs : Takeshi Agatsuma [Japon] ; Shigehisa Habe [Japon]Source :
- Parasitology [ 0031-1820 ] ; 1985-12.
Abstract
Lung flukes, Paragonimus ohirai, from Kinosaki, Japan, characterized by 3 electrophoretic variants, FF, FS and SS, of glutamic-oxaloacetic transaminase (GOT: EC 2.6.1.1) were crossed in the laboratory. In the case of a cross between FS and SS, a parent, FS, produced 9 SS and 16 FS clones in the offspring, numbers not significantly different from that expected (1:1) from Mendelian inheritance. From the other cross FS × FF, 20 clones originating from the respective 20 miracidia were obtained from a parent FS. The phenotype segregation ratio was 6 FF and 14 FS, which is not significantly different from Mendelian inheritance expectation. Only 3 clones were obtained from the other parent FF, but these segregated in a ratio of 2 FS: 1 FF. These breeding data indicate that the GOT isozymes of P. ohirai are controlled by 2 codominant alleles, GotF and Gots at a single locus whose products aggregate randomly, forming a dimer.
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DOI: 10.1017/S0031182000062727
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